Racks / Carriers Exposure to potentially toxic elements (PTEs) has been implicated in neurodevelopmental disorders and cognitive deficits in children.However, the extent of this association and the underlying mechanisms remain poorly understood.The objective of this systematic review is to consolidate the current body of research concerning the con
Angiogenesis is tightly regulated through the binding of vascular endothelial growth factors (VEGFs) to their receptors (VEGFRs).In this context, we showed that human VEGFR1 domain 2 Racks / Carriers crystallizes in the presence of Zn2+, Co2+ or Cu2+ as a dimer that forms via metal-ion interactions and interlocked hydrophobic surfaces.SAXS, NMR and
Rift Valley fever virus (RVFV) is a zoonotic arbovirus of the Phenuiviridae family.Infection causes abortions in pregnant animals, high mortality in neonate animals, and mild to severe symptoms in both people and animals.There is currently an ongoing effort to produce safe and efficacious veterinary vaccines against RVFV in livestock to protect aga
Abstract Background Eukaryotic cilia are complex, highly conserved microtubule-based organelles with a broad phylogenetic distribution.Cilia were present in the last eukaryotic common ancestor and many proteins involved in cilia function have been conserved through eukaryotic diversification.However, cilia have also been lost multiple times in diff